1998129-59-1
Chemical Structure
Peptide R analogue 10
- CAS No.: 1998129-59-1
- Formula:C41H59N13O9S2
- Molecular Weight:942.12
InChIKey: OCGLMIKXFRFGMM-IBBJOWKPSA-N
SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](CSSC[C@@H](C(O)=O)NC1=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H]1CC3=CC=CC=C3)=O)=O)=O)=O)=O)C
Biological Activity: Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer[1].
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Peptide R analogue 10 | 99.47% | Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer. | ||||||||||||||||||||
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Keywords
