20099-89-2
20099-89-2
Chemical Structure
4-(2-Bromoacetyl)benzonitrile
Synonym(s): 4-Cyanophenacyl bromide
- CAS No.: 20099-89-2
- Formula:C9H6BrNO
- Molecular Weight:224.05
IUPAC Name: 4-(2-bromoacetyl)benzonitrile
InChIKey: LJANCPRIUMHGJE-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C(CBr)=O)C=C1
Biological Activity: 4-(2-Bromoacetyl)benzonitrile (4-Cyanophenacyl bromide) can be used to the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-(2-Bromoacetyl)benzonitrile | 99.58% | 4-(2-Bromoacetyl)benzonitrile (4-Cyanophenacyl bromide) can be used to the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor. | ||||||||||||||||||||
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References
- [1]. Hao Li, et al. Development of a Practical Synthesis of STA-5312, a Novel Indolizine Oxalylamide Microtubule Inhibitor. Org. Process Res. Dev. 2007, 11, 2, 246–250
- [2]. Keizo Koya,et al. STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers. Cancer Res, Volume 45, 2004.
