2010159-56-3
Chemical Structure
(S,R,S)-AHPC-PEG3-NH2
Synonym(s): VH032-PEG3-NH2; VHL Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 5 Free Base
- CAS No.: 2010159-56-3
- Formula:C30H45N5O7S
- Molecular Weight:619.77
IUPAC Name: (2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: ZQKKNLXIQLXWLQ-ONBPZOJHSA-N
SMILES: O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
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(S,R,S)-AHPC-PEG3-NH2 | 99.26% | (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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Keywords
