2019131-11-2
2019131-11-2
Chemical Structure
PI3Kδ-IN-26
- CAS No.: 2019131-11-2
- Formula:C23H31N9O3
- Molecular Weight:481.55
SMILES: CN1C=C(C=N1)C2=NC3=C(C(N4CCOCC4)=N2)N=C(N3)C(N5CCC(CC5)N6CCOCC6)=O
Biological Activity: PI3Kδ-IN-26 (Compound 58) is a selective and orally active PI3Kδ inhibitor with an IC50 of 14 nM. PI3Kδ-IN-26 significantly attenuates the inflammatory responses in house dust mite (HDM) induced chronic asthma mouse models. PI3Kδ-IN-26 can be used for inflammatory, autoimmune and hyperproliferative diseases research[1].
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PI3Kδ-IN-26 | PI3Kδ-IN-26 (Compound 58) is a selective and orally active PI3Kδ inhibitor with an IC50 of 14 nM. PI3Kδ-IN-26 significantly attenuates the inflammatory responses in house dust mite (HDM) induced chronic asthma mouse models. PI3Kδ-IN-26 can be used for inflammatory, autoimmune and hyperproliferative diseases research. | |||||||||||||||||||||
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