PI3Kδ-IN-26
PI3Kδ-IN-26 (Compound 58) is a selective and orally active PI3Kδ inhibitor with an IC50 of 14 nM. PI3Kδ-IN-26 significantly attenuates the inflammatory responses in house dust mite (HDM) induced chronic asthma mouse models. PI3Kδ-IN-26 can be used for inflammatory, autoimmune and hyperproliferative diseases research.
For research use only. We do not sell to patients.
- CAS No.: 2019131-11-2
- Formula: C23H31N9O3
- Molecular Weight:481.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI3Kδ 14 nM (IC50) |
PI3Kα >1000 nM (IC50) |
PI3Kβ >10000 nM (IC50) |
PI3Kγ >1000 nM (IC50) |
Chemical Information
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CAS No. 2019131-11-2
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Molecular Weight 481.55
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Formula C23H31N9O3
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SMILES
CN1C=C(C=N1)C2=NC3=C(C(N4CCOCC4)=N2)N=C(N3)C(N5CCC(CC5)N6CCOCC6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PI3Kδ-IN-26 Related Classifications
HY-175734 Related Classifications
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