2055405-95-1
2055405-95-1
Chemical Structure
PIP4K-IN-a131
- CAS No.: 2055405-95-1
- Formula:C20H13N3
- Molecular Weight:295.34
IUPAC Name: (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile
InChIKey: GWWKEWLUVHLNEX-MHWRWJLKSA-N
SMILES: N#C/C(C1=CNC2=C1C=CC=C2)=C\C3=CC=CC4=C3C=CN=C4
Biological Activity: PIP4K-IN-a131 is PIP4K lipid kinases inhibitor, with IC50s of 1.9 μM and 0.6 μM for purified PIP4K2A and PIP4Ks, respectively. PIP4K-IN-a131 exhibits cancer-selective lethality via dual blockade of the lipid kinase PIP4Ks and mitotic pathways[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PIP4K-IN-a131 | 99.42% | PIP4K-IN-a131 is PIP4K lipid kinases inhibitor, with IC50s of 1.9 μM and 0.6 μM for purified PIP4K2A and PIP4Ks, respectively. PIP4K-IN-a131 exhibits cancer-selective lethality via dual blockade of the lipid kinase PIP4Ks and mitotic pathways. | ||||||||||||||||||||
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References
Keywords
