206552-86-5
Chemical Structure
2′-O-2-Propyn-1-ylguanosine
- CAS No.: 206552-86-5
- Formula:C13H15N5O5
- Molecular Weight:321.29
IUPAC Name: 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: VBIXIAQUDWOPDT-WOUKDFQISA-N
SMILES: O[C@H]1[C@@H](OCC#C)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO
Biological Activity: 2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2′-O-2-Propyn-1-ylguanosine | 98.46% | 2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
