2078047-99-9
Chemical Structure
CDK4/6-IN-15
- CAS No.: 2078047-99-9
- Formula:C21H27FN8S
- Molecular Weight:442.56
IUPAC Name: 5-(2-((5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)amino)-5-fluoropyrimidin-4-yl)-N,4-dimethylthiazol-2-amine
InChIKey: NAGFLZVMWVHHLW-UHFFFAOYSA-N
SMILES: CNC1=NC(C)=C(C2=NC(NC3=NC=C(N4CCC(N(C)C)CC4)C=C3)=NC=C2F)S1
Biological Activity: CDK4/6-IN-15 is an orally active and selective CDK4/6 inhibitor. CDK4/6-IN-15 potently inhibits cancer cells growth. CDK4/6-IN-15 arrests cell cycle at G1 phase and suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780 and E2 factor (E2F)-regulated gene expression[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDK4/6-IN-15 | 99.32% | CDK4/6-IN-15 is an orally active and selective CDK4/6 inhibitor. CDK4/6-IN-15 potently inhibits cancer cells growth. CDK4/6-IN-15 arrests cell cycle at G1 phase and suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780 and E2 factor (E2F)-regulated gene expression. | ||||||||||||||||||||
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Keywords
