2088333-58-6
Chemical Structure
RORγ-IN-2
- CAS No.: 2088333-58-6
- Formula:C28H32F3N5O4S2
- Molecular Weight:623.71
IUPAC Name: (S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-5'-methyl-1-((R)-1-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-2'-carboxamide
InChIKey: ILXLMNLDODDHOQ-ZWKOTPCHSA-N
SMILES: CCS(C(C=N1)=CC=C1CNC(C2=CC3=C(C4(O[C@H](C3)C)CCN(CC4)[C@@H](C5=CN=C(C(F)(F)F)N=C5)C)S2)=O)(=O)=O
Biological Activity: RORγ-IN-2 (Compound 22) is a RORγ inhibitor, with a Ki of 16.6 nM for hRORγ. RORγ-IN-2 can be used for the research of IL-17-dependent autoimmune diseases[1].
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RORγ-IN-2 | RORγ-IN-2 (Compound 22) is a RORγ inhibitor, with a Ki of 16.6 nM for hRORγ. RORγ-IN-2 can be used for the research of IL-17-dependent autoimmune diseases. | |||||||||||||||||||||
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Keywords