2095514-75-1
Chemical Structure
TP-030-1
- CAS No.: 2095514-75-1
- Formula:C23H22N4O3
- Molecular Weight:402.45
IUPAC Name: (S)-3-(2-benzyl-7-oxo-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one
InChIKey: MAHFVAHPQSLLJF-IBGZPJMESA-N
SMILES: O=C1[C@@H](N2CCC3=CN(CC4=CC=CC=C4)N=C3C2=O)COC5=CC=CC=C5N1C
Biological Activity: TP-030-1, a chemical probe, is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases[1].
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TP-030-1 | TP-030-1, a chemical probe, is an inhibitor of RIPK1. TP-030-1 inhibits hRIPK1 with a Ki value of 3.9 nM and inhibits mRIPK1 with an IC50 value of 4.2 μM. TP-030-1 can be used for the research of inflammatory diseases and neurodegenerative diseases. | |||||||||||||||||||||
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Keywords
