2097713-68-1
Chemical Structure
(R)-Odafosfamide
Synonym(s): OBI-3424; TH-3424; (R)-AST-3424
- CAS No.: 2097713-68-1
- Formula:C21H25N4O6P
- Molecular Weight:460.42
IUPAC Name: (R)-1-(3-(3-(dimethylcarbamoyl)phenoxy)-4-nitrophenyl)ethyl di(aziridin-1-yl)phosphinate
InChIKey: NWGZZGNICQFUHV-OAHLLOKOSA-N
SMILES: O=P(N1CC1)(N2CC2)O[C@@H](C3=CC=C([N+]([O-])=O)C(OC4=CC=CC(C(N(C)C)=O)=C4)=C3)C
Biological Activity: (R)-Odafosfamide (OBI-3424) is a proagent that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. (R)-Odafosfamide can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-Odafosfamide | 95.68% | (R)-Odafosfamide (OBI-3424) is a proagent that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. (R)-Odafosfamide can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research. | ||||||||||||||||||||
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