209977-58-2
209977-58-2
Chemical Structure
MeIQx-13C
Synonym(s): 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C
- No. CAS: 209977-58-2
- Formula:C1013CH11N5
- Molecular Weight:214.23
InChIKey: DVCCCQNKIYNAKB-KHWBWMQUSA-N
SMILES: CC1=NC2=C(N=C1)C=CC3=C2N=[13C](N3C)N
Biological Activity: MeIQx-13C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C) is the 13C-labeled MeIQx (HY-W355129). MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors[1][2].
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MeIQx-13C | MeIQx-13C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C) is the 13C-labeled MeIQx (HY-W355129). MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors. | |||||||||||||||||||||
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MeIQx-d3 | 99.0% | MeIQx-d3 is the deuterium labeled MeIQx (HY-W355129). MeIQx is a heterocyclic amine (HAs) compound and a dietary aromatic amine, which can bind covalently to hemoglobin. MeIQx is a mutagenic compound that induces liver tumors. | ||||||||||||||||||||
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MeIQx | 99.48% | MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors. | ||||||||||||||||||||
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References
- [1]. Lynch AM, et, al. The measurement of MeIQx adducts with mouse haemoglobin in vitro and in vivo: implications for human dosimetry. Carcinogenesis. 1991 Jun;12(6):1067-72. [Content Brief]
- [2]. Ohgaki H, et, al. Carcinogenicity in mice of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) from cooked foods. 1987 May;8(5):665-8.
