209984-56-5
209984-56-5
Chemical Structure
YO-01027
Synonym(s): Dibenzazepine; DBZ
- CAS No.: 209984-56-5
- Formula:C26H23F2N3O3
- Molecular Weight:463.48
IUPAC Name: (S)-2-(2-(3,5-difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide
InChIKey: QSHGISMANBKLQL-OWJWWREXSA-N
SMILES: O=C(N[C@@H](C)C(N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C)C1=O)=O)CC4=CC(F)=CC(F)=C4
Biological Activity: YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively.
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YO-01027 | 99.93% | YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively. | ||||||||||||||||||||
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YO-01027 (GMP) | YO-01027 (Dibenzazepine) (GMP) is YO-01027 (HY-13526) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. YO-01027 is a potent γ-secretase inhibitor. | |||||||||||||||||||||
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YO-01027 (Standard) | ≥98% | YO-01027 (Standard) is the analytical standard of YO-01027 (HY-13526). This product is intended for research and analytical applications. YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively. | ||||||||||||||||||||
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