2101200-52-4
2101200-52-4
Chemical Structure
Biotin-7-GMP
Synonym(s): 5'-Biotin-G-monophosphate
- CAS No.: 2101200-52-4
- Formula:C26H41N8O10PS
- Molecular Weight:688.69
InChIKey: VLZROYCITICIOM-DGWADGOTSA-N
SMILES: O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OCCCCCCNC(CCCC[C@H]4[C@]5([H])[C@](NC(N5)=O)([H])CS4)=O)(O)=O)O3)=C2N=C(N)N1
Biological Activity: Biotin-7-GMP (5'-Biotin-G-monophosphate) is a 5'-biotinylated guanosine monophosphate reagent. Biotin-7-GMP covalently links biotin to specific positions (G bases) of RNA molecules, enabling efficient and specific purification and detection of target RNAs through the ultra-stable binding between biotin and streptavidin[1][2].
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Biotin-7-GMP | Biotin-7-GMP (5'-Biotin-G-monophosphate) is a 5'-biotinylated guanosine monophosphate reagent. Biotin-7-GMP covalently links biotin to specific positions (G bases) of RNA molecules, enabling efficient and specific purification and detection of target RNAs through the ultra-stable binding between biotin and streptavidin. | |||||||||||||||||||||
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References
- [1]. Bompiani KM, et al. A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity. Journal of thrombosis and haemostasis : JTH. 2012 May;10(5):870-80. [Content Brief]
- [2]. Kahsai AW, et al. Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor. Nature chemical biology. 2016 Sep;12(9):709-16.
