2102170-43-2

GNE-2256 Chemical Structure
2102170-43-2

Chemical Structure

GNE-2256

  • CAS No.: 2102170-43-2
  • Formula:C24H27FN6O4
  • Molecular Weight:482.51

IUPAC Name: (R)-N-(2-(2-fluoro-3-hydroxy-3-methylbutyl)-6-morpholino-1-oxoisoindolin-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

InChIKey: AUYCSWFYKYVCLD-HXUWFJFHSA-N

SMILES: O=C(C1=C2N(C=CC=N2)N=C1)NC3=C(N4CCOCC4)C=C5C(CN(C5=O)C[C@@H](F)C(C)(O)C)=C3

Biological Activity: GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM)[1].

Cat. No. Product Name Purity Description Pricing
HY-148238 		GNE-2256 99.14% GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM).
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