2102170-43-2
2102170-43-2
Chemical Structure
GNE-2256
- CAS No.: 2102170-43-2
- Formula:C24H27FN6O4
- Molecular Weight:482.51
IUPAC Name: (R)-N-(2-(2-fluoro-3-hydroxy-3-methylbutyl)-6-morpholino-1-oxoisoindolin-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: AUYCSWFYKYVCLD-HXUWFJFHSA-N
SMILES: O=C(C1=C2N(C=CC=N2)N=C1)NC3=C(N4CCOCC4)C=C5C(CN(C5=O)C[C@@H](F)C(C)(O)C)=C3
Biological Activity: GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM)[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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GNE-2256 | 99.14% | GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM). | ||||||||||||||||||||
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