2123483-49-6
Chemical Structure
WNK-IN-11-d3
- CAS No.: 2123483-49-6
- Formula:C21H18D3Cl2N5OS
- Molecular Weight:465.41
IUPAC Name: (5-chloro-2-(2-((methyl-d3)amino)thiazol-4-yl)pyridin-4-yl)(4-(4-chlorobenzyl)piperazin-1-yl)methanone
InChIKey: MVXAYIXYYOVALX-FIBGUPNXSA-N
SMILES: O=C(N1CCN(CC1)CC2=CC=C(C=C2)Cl)C3=CC(C4=CSC(NC([2H])([2H])[2H])=N4)=NC=C3Cl
Biological Activity: WNK-IN-11-d3 is an orally active, selective and potent With-No-Lysine (WNK) kinase inhibitor. WNK-IN-11-d3 is effective at regulating cardiovascular homeostasis[1].
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WNK-IN-11-d3 | 99.84% | WNK-IN-11-d3 is an orally active, selective and potent With-No-Lysine (WNK) kinase inhibitor. WNK-IN-11-d3 is effective at regulating cardiovascular homeostasis. | ||||||||||||||||||||
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WNK-IN-11 | 99.71% | WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1. | ||||||||||||||||||||
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Keywords