213007-95-5
213007-95-5
Chemical Structure
Org37684
- CAS No.: 213007-95-5
- Formula:C14H20ClNO2
- Molecular Weight:269.77
IUPAC Name: (S)-3-((5-methoxy-2,3-dihydro-1H-inden-4-yl)oxy)pyrrolidine hydrochloride
InChIKey: KJEAKWPQCIAVGR-MERQFXBCSA-N
SMILES: COC1=C(O[C@@H]2CNCC2)C3=C(CCC3)C=C1.[H]Cl
Biological Activity: Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor[1].
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Org37684 | Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor. | |||||||||||||||||||||
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