2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Org37684

Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor.

For research use only. We do not sell to patients.

Org37684 Chemical Structure

Org37684 Chemical Structure

CAS No. : 213007-95-5

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Org37684 Related Antibodies

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Description

Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor[1].

In Vitro

Org37684 is an agonist at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Org37684 Related Antibodies
Molecular Weight

269.77

Formula

C14H20ClNO2
CAS No.
SMILES

COC1=C(O[C@@H]2CNCC2)C3=C(CCC3)C=C1.[H]Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Org37684 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Org37684213007-95-5Org 37684Org-376845-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorCHO-K1cellssubtypeInhibitorinhibitorinhibit

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