1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. Org37684

Org37684 

Cat. No.: HY-103120
Handling Instructions

Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor.

For research use only. We do not sell to patients.

Org37684 Chemical Structure

Org37684 Chemical Structure

CAS No. : 213007-95-5

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Description

Org37684 is a highly potent 5-HT2C receptor agonist (pEC50=8.17). Org37684 exhibits a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. Its selectivity for the 5-HT2C receptor is approximately 2.5 times over the 5-HT2B (pEC50=7.96) and ten times for the 5-HT2A (pEC50=7.11) receptor[1].

In Vitro

Org37684 is an agonist at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

269.77

Formula

C₁₄H₂₀ClNO₂

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Org37684
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HY-103120
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