213481-12-0
213481-12-0
Chemical Structure
BPD
- CAS No.: 213481-12-0
- Formula:C17H10O5
- Molecular Weight:294.26
InChIKey: IMHGOAWBSJVILI-UHFFFAOYSA-N
SMILES: O=C1OC(C(C2=CC3=C(OCO3)C=C2)=C1C4=CC=CC=C4)=O
Biological Activity: BPD is a COX-2 and TAK1-NF-κB inhibitor, with an IC50 of 18.5 μM for COX-2. BPD inhibits the expression of iNOS, TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death[1].
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BPD | BPD is a COX-2 and TAK1-NF-κB inhibitor, with an IC50 of 18.5 μM for COX-2. BPD inhibits the expression of iNOS, TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death. | |||||||||||||||||||||
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