2143089-35-2

LT-540-717 Chemical Structure
2143089-35-2

Chemical Structure

LT-540-717

  • CAS No.: 2143089-35-2
  • Formula:C24H24N8O2
  • Molecular Weight:456.50

InChIKey: RSZBDSJQRIEBFQ-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(N2CCNCC2)C=C1)C3=NNC=C3NC4=NC=NC(OC5=CC=CC=C5)=C4

Biological Activity: LT-540-717 (compound 32) is a potent FLT3 inhibitor (IC50=0.62 nM) with antiproliferative activity. LT-540-717 also inhibits several acquired FLT3 mutations, FLT3 (ITD, D835V), FLT3 (ITD, F691L), FLT3 (D835Y) and FLT3 (D835V). LT-540-717 has potential to be an anti-AML agent[1].

Cat. No. Product Name Purity Description Pricing
HY-155594 		LT-540-717 LT-540-717 (compound 32) is a potent FLT3 inhibitor (IC50=0.62 nM) with antiproliferative activity. LT-540-717 also inhibits several acquired FLT3 mutations, FLT3 (ITD, D835V), FLT3 (ITD, F691L), FLT3 (D835Y) and FLT3 (D835V). LT-540-717 has potential to be an anti-AML agent.
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