216308-19-9
216308-19-9
Chemical Structure
DB293
- CAS No.: 216308-19-9
- Formula:C19H16N6O
- Molecular Weight:344.37
InChIKey: LXJNJISEUJIGFP-UHFFFAOYSA-N
SMILES: N=C(C1=CC=C(C2=CC=C(C3=NC4=CC=C(C(N)=N)C=C4N3)O2)C=C1)N
Biological Activity: DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences[1].
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DB293 | DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences. | |||||||||||||||||||||
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