2170836-81-2
Chemical Structure
MX106
- CAS No.: 2170836-81-2
- Formula:C25H30N2O2
- Molecular Weight:390.53
IUPAC Name: 5-(((4-isopropylbenzyl)oxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol
InChIKey: NNIPSBLMEGJOFO-UHFFFAOYSA-N
SMILES: OC1=C2N=CC=CC2=C(C=C1CN3CCCC3)COCC4=CC=C(C=C4)C(C)C
Biological Activity: MX106 is a survivin inhibitor and an analog of UC-112 (HY-12842). MX106 inhibits the expression of survivin both in vitro and in vivo. MX106 suppresses the proliferation of human melanoma cells, epidermoid carcinoma cells and colon cancer cells, and also exerts inhibitory effects on multidrug-resistant cell lines overexpressing P-glycoprotein[1].
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MX106 | MX106 is a survivin inhibitor and an analog of UC-112 (HY-12842). MX106 inhibits the expression of survivin both in vitro and in vivo. MX106 suppresses the proliferation of human melanoma cells, epidermoid carcinoma cells and colon cancer cells, and also exerts inhibitory effects on multidrug-resistant cell lines overexpressing P-glycoprotein. | |||||||||||||||||||||
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Keywords
