219714-96-2
Chemical Structure
Penoxsulam
- CAS No.: 219714-96-2
- Formula:C16H14F5N5O5S
- Molecular Weight:483.37
IUPAC Name: 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide
InChIKey: SYJGKVOENHZYMQ-UHFFFAOYSA-N
SMILES: O=S(C1=C(C(F)(F)F)C=CC=C1OCC(F)F)(NC2=NN3C(OC)=NC=C(OC)C3=N2)=O
Biological Activity: Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections[1][2].
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Penoxsulam | Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections. | |||||||||||||||||||||
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- [1]. Agnew-Francis KA, et al. Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris. ACS Infect Dis. 2020 Nov 13;6(11):2901-2912. [Content Brief]
- [2]. Jabusch TW, et al. Partitioning of penoxsulam, a new sulfonamide herbicide. J Agric Food Chem. 2005 Sep 7;53(18):7179-83. [Content Brief]
Keywords
