219920-81-7
Chemical Structure
Bisnorcymserine
Synonym(s): N1,N8-Bisnorcymserine; (-)-Bisnorcymserine
- CAS No.: 219920-81-7
- Formula:C21H25N3O2
- Molecular Weight:351.44
IUPAC Name: (3aS,8aR)-3a-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-isopropylphenyl)carbamate
InChIKey: ZIGIADNCAWZUAB-CTNGQTDRSA-N
SMILES: O=C(NC1=CC=C(C=C1)C(C)C)OC2=CC3=C(C=C2)N[C@@]4([C@]3(CCN4)C)[H]
Biological Activity: Bisnorcymserine ((-)-Bisnorcymserine) is an inhibitor for butyrylcholinesterase (BChE) with an IC50 of 0.228 nM. Bisnorcymserine reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates the Alzheimer’s Disease in elderly rat models. Bisnorcymserine is blood-brain barrier penetrate[1].
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Bisnorcymserine | Bisnorcymserine ((-)-Bisnorcymserine) is an inhibitor for butyrylcholinesterase (BChE) with an IC50 of 0.228 nM. Bisnorcymserine reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates the Alzheimer’s Disease in elderly rat models. Bisnorcymserine is blood-brain barrier penetrate. | |||||||||||||||||||||
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