220644-02-0
Chemical Structure
Z-VA-DL-D-FMK
Synonym(s): Z-VA-DL-D(OH)-FMK
- CAS No.: 220644-02-0
- Formula:C21H28FN3O7
- Molecular Weight:453.46
IUPAC Name: (5S,8S)-11-(2-fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oic acid
InChIKey: SUUHZYLYARUNIA-LWSHRDBSSA-N
SMILES: O=C(CF)C(NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)CC(O)=O
Biological Activity: Z-VA-DL-D-FMK (Z-VA-DL-D(OH)-FMK) is an inhibitor for caspase[1]. Z-VA-DL-D-FMK binds irreversibly to caspases, increases the sensitivity of TNF-α, and activates HIV replication in infected T cell ACH-2[1].
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Z-VA-DL-D-FMK | Z-VA-DL-D-FMK (Z-VA-DL-D(OH)-FMK) is an inhibitor for caspase. Z-VA-DL-D-FMK binds irreversibly to caspases, increases the sensitivity of TNF-α, and activates HIV replication in infected T cell ACH-2. | |||||||||||||||||||||
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Keywords