221362-74-9
221362-74-9
Chemical Structure
(R)-Isosakuranetin
- CAS No.: 221362-74-9
- Formula:C16H14O5
- Molecular Weight:286.28
SMILES: OC1=C2C(O[C@H](CC2=O)C3=CC=C(OC)C=C3)=CC(O)=C1
Biological Activity: (R)-Isosakuranetin is an isomer of Isosakuranetin (HY-N2131). Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3].
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(R)-Isosakuranetin | 99.56% | (R)-Isosakuranetin is an isomer of Isosakuranetin (HY-N2131). Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker. | ||||||||||||||||||||
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References
- [1]. Drira R, et al. Isosakuranetin, a 4'-O-methylated flavonoid, stimulates melanogenesis in B16BL6 murine melanoma cells. Life Sci. 2015 Dec 15;143:43-9. [Content Brief]
- [2]. Jia S, et al. Antinociceptive Effects of Isosakuranetin in a Rat Model of Peripheral Neuropathy. Pharmacology. 2017;100(3-4):201-207. [Content Brief]
- [3]. Straub I, et al. Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo. Mol Pharmacol. 2013 Nov;84(5):736-50. [Content Brief]
Keywords
