22200-69-7
22200-69-7
Chemical Structure
Seriniquinone
- CAS No.: 22200-69-7
- Formula:C20H8O4S
- Molecular Weight:344.34
IUPAC Name: dinaphtho[2,3-b:2',3'-d]thiophene-5,7,12,13-tetraone
InChIKey: PWUWIMAXHCTYJA-UHFFFAOYSA-N
SMILES: O=C(C1=C2C(C3=O)=C(C(C4=C3C=CC=C4)=O)S1)C5=C(C=CC=C5)C2=O
Biological Activity: Seriniquinone, a selective anti-melanoma agent that targets Dermcidin, induces cell death by autophagocytosis. Seriniquinone is a metabolite produced by a rare marine bacterium of the genus Serinicoccus[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Seriniquinone | 98.39% | Seriniquinone, a selective anti-melanoma agent that targets Dermcidin, induces cell death by autophagocytosis. Seriniquinone is a metabolite produced by a rare marine bacterium of the genus Serinicoccus. | ||||||||||||||||||||
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References
- [1]. Lynnie Trzoss, et al. Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14687-92. [Content Brief]
- [2]. Amanda S Hirata, et al. Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas. Molecules. 2021 Dec 4;26(23):7362. [Content Brief]
