22203-98-1
22203-98-1
Chemical Structure
SARS-CoV-2-IN-14
- CAS No.: 22203-98-1
- Formula:C13H9Cl2NO2
- Molecular Weight:282.12
IUPAC Name: 5-chloro-N-(3-chlorophenyl)-2-hydroxybenzamide
InChIKey: NXDGLRGDIKDWIF-UHFFFAOYSA-N
SMILES: O=C(C1=C(C=CC(Cl)=C1)O)NC2=CC(Cl)=CC=C2
Biological Activity: SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SARS-CoV-2-IN-14 | 99.02% | SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
