2225902-88-3
Chemical Structure
Nek2-IN-4
- CAS No.: 2225902-88-3
- Formula:C28H27F3N6O2S
- Molecular Weight:568.61
IUPAC Name: (S)-5-(7-(1-(2-(dimethylamino)ethyl)-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide
InChIKey: BQODGOMHYSMCGK-KRWDZBQOSA-N
SMILES: O=C(C1=C(O[C@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N
Biological Activity: Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1].
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Nek2-IN-4 | Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer. | |||||||||||||||||||||
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Keywords