Nek2-IN-4
Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer.
For research use only. We do not sell to patients.
- CAS No.: 2225902-88-3
- Formula: C28H27F3N6O2S
- Molecular Weight:568.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NEK2 15 nM (IC50) |
Nek2-IN-4 (72 h) inhibits cell growth with IC50s of 0.064, 0.031, 0.161 µM for AsPC-1, PL45, MIA PaCa-2 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:AsPC-1, PL45, MIA PaCa-2 cells
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Concentration:
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Incubation Time:72 h
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Result:Showed antiproliferative activity with IC50s of 0.064, 0.031, 0.161 µM for AsPC-1, PL45, MIA PaCa-2 cells, respectively.
Chemical Information
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CAS No. 2225902-88-3
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Molecular Weight 568.61
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Formula C28H27F3N6O2S
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SMILES
O=C(C1=C(O[C@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nek2-IN-4 Related Classifications
HY-137046 Related Classifications
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