2226178-35-2
2226178-35-2
Chemical Structure
AB-452
- CAS. Nr.: 2226178-35-2
- Formula:C21H26N2O6
- Molecular Weight:402.44
InChIKey: UZKFYFNINMJEGT-HNNXBMFYSA-N
SMILES: CC([C@H]1N2C(C3=NC(OC)=C(OCCCOC)C=C3C1)=CC(C(C(O)=O)=C2)=O)C
Biological Activity: AB-452, a Dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer. AB-452 inhibits PAPD5/7 proteins in vitro with good in vivo efficacy in a chronic HBV mouse model[1].
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AB-452 | AB-452, a Dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer. AB-452 inhibits PAPD5/7 proteins in vitro with good in vivo efficacy in a chronic HBV mouse model. | |||||||||||||||||||||
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