222629-77-8
222629-77-8
Chemical Structure
Antidesmone
- CAS No.: 222629-77-8
- Formula:C19H29NO3
- Molecular Weight:319.44
IUPAC Name: (S)-3-methoxy-2-methyl-5-octyl-1,5,6,7-tetrahydroquinoline-4,8-dione
InChIKey: SJWGGIJOUKBIPF-AWEZNQCLSA-N
SMILES: O=C1C(OC)=C(C)NC2=C1[C@@H](CCCCCCCC)CCC2=O
Biological Activity: Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1]. Antidesmone can prevent acute lung injury in vivo via inhibiting MAPK and NF-κb activities[2].
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Antidesmone | Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum. Antidesmone can prevent acute lung injury in vivo via inhibiting MAPK and NF-κb activities. | |||||||||||||||||||||
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References
- [1]. Lu X, et al. Antidesmone, a unique tetrahydroquinoline alkaloid, prevents acute lung injury via regulating MAPK and NF-κB activities. Int Immunopharmacol. 2017 Apr;45:34-42. [Content Brief]
- [2]. Buske, et al. Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae). Tetrahedron, 55(4), 1079–1086.
Keywords
