2230854-98-3
Chemical Structure
ARN21929
- CAS No.: 2230854-98-3
- Formula:C18H16FN5
- Molecular Weight:321.35
InChIKey: KTMFKCBSMORHOY-UHFFFAOYSA-N
SMILES: FC1=C(C=CC=C1)NC2=NC(C3=CC=NC=C3)=NC4=C2CNCC4
Biological Activity: ARN21929 is a Topoisomerase II inhibitor with an IC50 of 4.5 μM. ARN21929 exhibits excellent kinetic and thermodynamic solubility as well as metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. ARN21929 can be used in the study of cancer[1].
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ARN21929 | 99.63% | ARN21929 is a Topoisomerase II inhibitor with an IC50 of 4.5 μM. ARN21929 exhibits excellent kinetic and thermodynamic solubility as well as metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. ARN21929 can be used in the study of cancer. | ||||||||||||||||||||
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Keywords