223420-41-5
223420-41-5
Chemical Structure
6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin
- CAS No.: 223420-41-5
- Formula:C10H7BrO4
- Molecular Weight:271.06
IUPAC Name: 6-bromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one
InChIKey: IIDQAAJTECOGEG-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(CO)=C1)C=C(Br)C(O)=C2
Biological Activity: 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin is a photosensitive cage like ceramide. 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin can release active ceramides under light exposure. 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin can be used for research on drug release with high spatiotemporal precision[1][2].
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6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin | 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin is a photosensitive cage like ceramide. 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin can release active ceramides under light exposure. 6-Bromo-7-hydroxy-4-(hydroxymethyl)coumarin can be used for research on drug release with high spatiotemporal precision. | |||||||||||||||||||||
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References
- [1]. Kim YA, et al. A new tool to assess ceramide bioactivity: 6-bromo-7-hydroxycoumarinyl-caged ceramide. Chem Commun (Camb). 2011 Aug 28;47(32):9236-8. [Content Brief]
- [2]. Perdicakis B, et al. Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor. Bioorg Med Chem. 2005 Jan 3;13(1):47-57. [Content Brief]
