2234285-81-3
2234285-81-3
Chemical Structure
IDH1 Inhibitor 1
- CAS No.: 2234285-81-3
- Formula:C20H18F4N6O2
- Molecular Weight:450.39
IUPAC Name: (R)-4-(fluoromethyl)-3-(2-(((S)-1-(1-(4-(trifluoromethyl)phenyl)-1H-imidazol-4-yl)ethyl)amino)pyrimidin-4-yl)oxazolidin-2-one
InChIKey: ULTZLMKTFYRMFK-WFASDCNBSA-N
SMILES: C[C@H](NC1=NC(N2[C@@H](CF)COC2=O)=CC=N1)C(N=C3)=CN3C4=CC=C(C(F)(F)F)C=C4
Biological Activity: IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant IDH1 inhibitor with IC50s of 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT, respectively[1]. Anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IDH1 Inhibitor 1 | 99.96% | IDH1 Inhibitor 1 is a potent, orally bioavailable, brain-penetrant and selective mutant IDH1 inhibitor with IC50s of 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT, respectively. Anticancer activity. | ||||||||||||||||||||
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References
Keywords
