223465-78-9
Chemical Structure
Arborcandin B
- CAS No.: 223465-78-9
- Formula:C58H103N13O18
- Molecular Weight:1270.51
InChIKey: VZFZGDKKOUEQOZ-PHEFGGHDSA-N
SMILES: NC(C(O)CC1C(N[C@](C(N[C@@](C(NC(C(NCC(NCCC(NC(C(N[C@@H](C(N[C@H](C(N[C@@H](C(N1)=O)C)=O)CC(N)=O)=O)CC(N)=O)=O)CCCCCCCC(O)CCCCC)=O)=O)=O)CCC(O)CCCCCCCCC)=O)([H])[C@H](O)C)=O)([H])[C@H](O)C)=O)=O
Biological Activity: Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida[1].
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Arborcandin B | Arborcandin B is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin B exhibits IC50 values of 0.30 μg/mL and 0.025 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin B has an MIC of 2-4 μg/mL against the genus Candida. | |||||||||||||||||||||
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Keywords
