2234874-68-9
Chemical Structure
αvβ1 integrin-IN-2
- CAS No.: 2234874-68-9
- Formula:C29H38N4O4
- Molecular Weight:506.64
InChIKey: CIKDYWXRZXYDDM-UHFFFAOYSA-N
SMILES: O=C(CC(CC1=NN(C)C(OCCC2=CC=C3C(N2)=NCCC3)=C1)C4=CC(C(C)(C)C)=CC=C4OC)O
Biological Activity: αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay[1].
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αvβ1 integrin-IN-2 | αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM,and 33 nM,respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ,,IC50s of 380 nM (ανβ3),280 nM (ανβ5),230 nM (ανβ6),87 nM (ανβ8),respectively,in SPRA assay. | |||||||||||||||||||||
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Keywords