2247064-44-2
Chemical Structure
ASK1-IN-11
- CAS No.: 2247064-44-2
- Formula:C23H22N6O3
- Molecular Weight:430.46
SMILES: O=C1C2=CC=C(C(N3CCOCC3)=O)C=C2CN1C4=NC(C5=NN=CN5C6CC6)=CC=C4
Biological Activity: ASK1-IN-11 (Compound 7) is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 <200 nM. ASK1-IN-11 also shows inhibitory activities to TNF-α, MYLK/MLCK Kinase and hERG potassium channels . ASK1-IN-11 can be used for the research of inflammation[1].
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ASK1-IN-11 | ASK1-IN-11 (Compound 7) is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 <200 nM. ASK1-IN-11 also shows inhibitory activities to TNF-α, MYLK/MLCK Kinase and hERG potassium channels . ASK1-IN-11 can be used for the research of inflammation. | |||||||||||||||||||||
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Keywords