2253947-47-4
2253947-47-4
Chemical Structure
BMS-986235
Synonym(s): LAR-1219
- CAS. Nr.: 2253947-47-4
- Formula:C18H17F2N3O3
- Molecular Weight:361.34
IUPAC Name: 1-((3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea
InChIKey: FJZNNKJZHQFMCK-LRDDRELGSA-N
SMILES: O=C(NC1=CC=CC=C1)N[C@@H]2C(NC[C@H]2C3=C(F)C=C(OC)C=C3F)=O
Biological Activity: BMS-986235 (LAR-1219) is a selective, orally active formyl peptide receptor 2 (FPR2) agonist, with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 has potential for the prevention of heart failure[1].
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BMS-986235 | 99.84% | BMS-986235 (LAR-1219) is a selective, orally active formyl peptide receptor 2 (FPR2) agonist, with EC50s of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 has potential for the prevention of heart failure. | ||||||||||||||||||||
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