22584-04-9
Chemical Structure
AHR-1911
Synonym(s): 10-Undecen-1-yl-thiopseudourea iodide
- CAS No.: 22584-04-9
- Formula:C12H25IN2S
- Molecular Weight:356.31
IUPAC Name: undec-10-en-1-yl carbamimidothioate hydroiodide
InChIKey: INDZTCRIYSRWOH-UHFFFAOYSA-N
SMILES: C=CCCCCCCCCCSC(N)=N.[H]I
Biological Activity: AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis[1][2].
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AHR-1911 | 99.66% | AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis. | ||||||||||||||||||||
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- [1]. Fuenmayor L, et al. Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. Proc Soc Exp Biol Med. 1973 Jun;143(2):568-71. [Content Brief]
- [2]. González-Cadavid NF, et al. Inhibition of translation in liver polyribosomes by a new substituted thiopseudourea with antitumour action. Biochem J. 1974 Feb;138(2):129-41. [Content Brief]
Keywords
