2259308-68-2
2259308-68-2
Chemical Structure
STING agonist-11
- CAS No.: 2259308-68-2
- Formula:C25H20ClF4N3O2
- Molecular Weight:505.89
IUPAC Name: (S)-1-(2-chloro-6-fluorobenzyl)-3,4-dimethyl-2-oxo-N-(2,4,6-trifluorobenzyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide
InChIKey: DQAVYPSHLPBIAS-ZDUSSCGKSA-N
SMILES: O=C(C1=CC2=C(C=C1)[C@H](C)N(C)C(N2CC3=C(F)C=CC=C3Cl)=O)NCC4=C(F)C=C(F)C=C4F
Biological Activity: STING agonist-11 (Compound 92) is a potent small molecule cyclic urea activator of STING with EC50 of 18 nM. Activation of STING is a highly promising approach in immunotherapy[1].
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STING agonist-11 | STING agonist-11 (Compound 92) is a potent small molecule cyclic urea activator of STING with EC50 of 18 nM. Activation of STING is a highly promising approach in immunotherapy. | |||||||||||||||||||||
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