2259641-42-2
2259641-42-2
Chemical Structure
Ep300/CREBBP-IN-4
- CAS No.: 2259641-42-2
- Formula:C23H22F3N5O3
- Molecular Weight:473.45
IUPAC Name: (2R,4R)-1-(3,3-difluoro-1-(4-methoxyphenyl)cyclobutane-1-carbonyl)-4-fluoro-N-(1H-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide
InChIKey: TURGXTFEXLEVEN-RDTXWAMCSA-N
SMILES: O=C(N1[C@H](C[C@H](C1)F)C(NC2=CC=C(NN=C3)C3=N2)=O)C4(C5=CC=C(C=C5)OC)CC(F)(C4)F
Biological Activity: Ep300/CREBBP-IN-4 (Example 56) is a potent Ep300 and CREBBP inhibitor with IC50s of 0.024 and 0.064 μM, respectively. Ep300/CREBBP-IN-4 can be used for the research of cancer[1].
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Ep300/CREBBP-IN-4 | Ep300/CREBBP-IN-4 (Example 56) is a potent Ep300 and CREBBP inhibitor with IC50s of 0.024 and 0.064 μM, respectively. Ep300/CREBBP-IN-4 can be used for the research of cancer. | |||||||||||||||||||||
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