2268794-52-9
Chemical Structure
HPK1-IN-27
- CAS No.: 2268794-52-9
- Formula:C26H23F3N4O4
- Molecular Weight:512.48
IUPAC Name: (2-((3,5-difluoro-4-((3-(2-fluoro-4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)amino)-5-methyl-5,6-dihydro-4H-1,3-oxazin-5-yl)methanol
InChIKey: SIVPOEPNFMZRLH-UHFFFAOYSA-N
SMILES: OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1
Biological Activity: HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38)[1].
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HPK1-IN-27 | HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38). | |||||||||||||||||||||
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