2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-27

HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38).

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HPK1-IN-27 Chemical Structure

HPK1-IN-27 Chemical Structure

CAS No. : 2268794-52-9

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HPK1-IN-27 Related Antibodies

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Description

HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38)[1].

Molecular Weight

512.48

Formula

C26H23F3N4O4
CAS No.
SMILES

OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPK1-IN-27 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-272268794-52-9MAP4KMAPK Kinase Kinase KinaseHPK1MAP4K1cancerserinethreonine kinasegerminal center kinaseInhibitorinhibitorinhibit

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