2271348-89-9
2271348-89-9
Chemical Structure
SMARCA2/4-ligand-5
- CAS No.: 2271348-89-9
- Formula:C20H13ClN4O3
- Molecular Weight:392.80
InChIKey: ATBXCKLXXDLBAC-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C#CC2=CC=CC(C(O)=O)=C2)=NC=C1)NC3=CC(Cl)=NC=C3
Biological Activity: SMARCA2/4-ligand-5 is a SMARCA2/4 ligand for PROTAC SMARCA2/4 degrader-37 (Example 4). PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM[1].
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SMARCA2/4-ligand-5 | SMARCA2/4-ligand-5 is a SMARCA2/4 ligand for PROTAC SMARCA2/4 degrader-37 (Example 4). PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM. | |||||||||||||||||||||
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