2280037-51-4
2280037-51-4
Chemical Structure
Bobcat339
- CAS No.: 2280037-51-4
- Formula:C16H12ClN3O
- Molecular Weight:297.74
IUPAC Name: 1-([1,1'-biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one
InChIKey: QMGYGOOYCNTEQO-UHFFFAOYSA-N
SMILES: NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O
Biological Activity: Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1].
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Bobcat339 | 99.30% | Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription. | ||||||||||||||||||||
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References
Keywords
