2305789-66-4
Chemical Structure
ASM-IN-2
- CAS No.: 2305789-66-4
- Formula:C16H11BrClN3O2
- Molecular Weight:392.63
InChIKey: BWHLCGVVTKWFAA-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C(C2=CC=C(C=C2)Br)=C1)C3=CC=C(C=C3)Cl)NO
Biological Activity: ASM-IN-2 (Compound 46) is a potent ASM inhibitor with an IC50 value of 0.87 μM, displaying good drug-like properties. ASM-IN-2 involves in multiple antidepressant mechanisms of actionin, which are associated with a decline of ceramide. It demostrates remarkable antidepressant effects in the CUMS-induced mouse, which is promising for research in the field of antidepressant drugs[1].
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ASM-IN-2 | ASM-IN-2 (Compound 46) is a potent ASM inhibitor with an IC50 value of 0.87 μM, displaying good drug-like properties. ASM-IN-2 involves in multiple antidepressant mechanisms of actionin, which are associated with a decline of ceramide. It demostrates remarkable antidepressant effects in the CUMS-induced mouse, which is promising for research in the field of antidepressant drugs. | |||||||||||||||||||||
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Keywords