2305936-70-1
2305936-70-1
Chemical Structure
Pomalidomide 4'-alkylC8-acid
- CAS No.: 2305936-70-1
- Formula:C22H27N3O6
- Molecular Weight:429.47
IUPAC Name: 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid
InChIKey: OGMJVYCYINHWEJ-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-Linker conjugate containing Pomalidomide (HY-10984). Pomalidomide is a third-generation immunomodulator that acts like a molecular glue. Pomalidomide interacts with the E3 ligase cereblon to induce degradation of the essential Ikaros transcription factor[1].
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Pomalidomide 4'-alkylC8-acid | Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-Linker conjugate containing Pomalidomide (HY-10984). Pomalidomide is a third-generation immunomodulator that acts like a molecular glue. Pomalidomide interacts with the E3 ligase cereblon to induce degradation of the essential Ikaros transcription factor. | |||||||||||||||||||||
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