23095-76-3
23095-76-3
Chemical Structure
(R)-(-)-Chlorpheniramine maleate
- CAS No.: 23095-76-3
- Formula:C20H23ClN2O4
- Molecular Weight:390.86
IUPAC Name: (R)-3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate
InChIKey: DBAKFASWICGISY-HFNHQGOYSA-N
SMILES: OC(/C=C\C(O)=O)=O.CN(C)CC[C@@H](C1=CC=CC=N1)C2=CC=C(C=C2)Cl
Biological Activity: (R)-(-)-Chlorpheniramine maleate is an enantiomer of Chlorpheniramine maleate (HY-B0286A). Chlorpheniramine maleate is a H1 antihistamines. (R)-(-)-Chlorpheniramine maleate can be used for allergic diseases such as rhinitis and urticaria research[1][2].
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(R)-(-)-Chlorpheniramine maleate | (R)-(-)-Chlorpheniramine maleate is an enantiomer of Chlorpheniramine maleate (HY-B0286A). Chlorpheniramine maleate is a H1 antihistamines. (R)-(-)-Chlorpheniramine maleate can be used for allergic diseases such as rhinitis and urticaria research. | |||||||||||||||||||||
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References
- [1]. Sakurai E, et al. The optical resolution of racemic chlorpheniramine and its stereoselective pharmacokinetics in rat plasma. J Pharm Pharmacol. 1992 Jan;44(1):44-7. [Content Brief]
- [2]. Kim J, et al. Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells. Eur J Pharmacol. 2017 Mar 5;798:122-128. [Content Brief]
