2320427-95-8
2320427-95-8
Chemical Structure
EAD1 TFA
- CAS No.: 2320427-95-8
- Formula:C26H28Cl2F3N7O2
- Molecular Weight:598.45
InChIKey: LZSPLENCPSTSGU-UHFFFAOYSA-N
SMILES: O=C(C(F)(F)F)O.ClC1=CC=C(CN2N=NC(CNCCN(CCNC3=C4C=CC(Cl)=CC4=NC=C3)C)=C2)C=C1
Biological Activity: EAD1 TFA is a Chloroquine (HY-17589A) analog with anticancer activity. EAD1 TFA blocks autophagy, leading to the intracellular accumulation of autophagosome-related proteins LC3-II and p62. EAD1 TFA induces cancer cell apoptosis and inhibits cancer cell proliferation. EAD1 TFA can be used in the research of lung cancer and pancreatic cancer[1].
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EAD1 TFA | EAD1 TFA is a Chloroquine (HY-17589A) analog with anticancer activity. EAD1 TFA blocks autophagy, leading to the intracellular accumulation of autophagosome-related proteins LC3-II and p62. EAD1 TFA induces cancer cell apoptosis and inhibits cancer cell proliferation. EAD1 TFA can be used in the research of lung cancer and pancreatic cancer. | |||||||||||||||||||||
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References
Keywords
